2-bromo-5-methyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine
Thiazolo[5,4-c]pyridine, 2-bromo-4,5,6,7-tetrahydro-5-methyl-
CAS: 143150-92-9
Molecular Formula: C7H9BrN2S
2-bromo-5-methyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine - Names and Identifiers
2-bromo-5-methyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine - Physico-chemical Properties
| Molecular Formula | C7H9BrN2S |
| Molar Mass | 233.13 |
| Density | 1.594±0.06 g/cm3(Predicted) |
| Boling Point | 286.4±30.0 °C(Predicted) |
| Solubility | Acetonitrile (Slightly), Chloroform (Slightly) |
| Appearance | Solid |
| Color | Grey |
| pKa | 6.41±0.20(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
2-bromo-5-methyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine - Introduction
2-Bromo-5-methyl-4, 5,6, 7-thiazolo [5,4-c] pyridine is an organic compound, also known as TCB or TCTP.
Nature:
-Appearance: TCB is a colorless to pale yellow solid.
-Melting point: The melting point of TCB is about 80-84°C.
-Solubility: TCB is soluble in common organic solvents such as ethanol, methanol and dichloromethane.
-Stability: TCB is relatively stable, but may decompose under high temperature, strong acid or strong alkali conditions.
Use:
-Pesticide: TCB is a broad-spectrum pesticide that can be used to control pests on crops.
-Pharmaceutical: TCB can also be used as an intermediate for the synthesis of certain pharmaceutical products.
Preparation Method:
The preparation method of TCB usually includes the following steps:
1. Synthesis of 4,5,6,7-thiazolidine. This process typically uses the reaction of hydrogen sulfide and a hydrocarbon containing an amine.
2. Synthesis of 2-bromo -5-methyl -4,5,6,7-thiazolidine. One common method is to use bromine and methyl chloride under alkaline conditions.
3.2-bromo-5-methyl-4, 5,6, 7-thiazolidine is reacted with a pyridine compound as a raw material to produce the final 2-bromo-5-methyl-4, 5,6, 7-thiazolo [5,4-C] pyridine.
Safety Information:
- TCB is an organic bromine compound that may have toxic and long-term cumulative effects on the environment. Follow the relevant hazardous material handling guidelines for use and handling.
-Wear appropriate protective gloves, eye and respiratory devices when operating the TCB.
- TCB should be stored in a dry, cool, well-ventilated place, away from ignition and other flammable substances.
-In the event of accidental contact with TCB, immediately rinse the skin with plenty of water and seek medical assistance. If TCB is inhaled or taken by mistake, take the patient to the hospital immediately.
Nature:
-Appearance: TCB is a colorless to pale yellow solid.
-Melting point: The melting point of TCB is about 80-84°C.
-Solubility: TCB is soluble in common organic solvents such as ethanol, methanol and dichloromethane.
-Stability: TCB is relatively stable, but may decompose under high temperature, strong acid or strong alkali conditions.
Use:
-Pesticide: TCB is a broad-spectrum pesticide that can be used to control pests on crops.
-Pharmaceutical: TCB can also be used as an intermediate for the synthesis of certain pharmaceutical products.
Preparation Method:
The preparation method of TCB usually includes the following steps:
1. Synthesis of 4,5,6,7-thiazolidine. This process typically uses the reaction of hydrogen sulfide and a hydrocarbon containing an amine.
2. Synthesis of 2-bromo -5-methyl -4,5,6,7-thiazolidine. One common method is to use bromine and methyl chloride under alkaline conditions.
3.2-bromo-5-methyl-4, 5,6, 7-thiazolidine is reacted with a pyridine compound as a raw material to produce the final 2-bromo-5-methyl-4, 5,6, 7-thiazolo [5,4-C] pyridine.
Safety Information:
- TCB is an organic bromine compound that may have toxic and long-term cumulative effects on the environment. Follow the relevant hazardous material handling guidelines for use and handling.
-Wear appropriate protective gloves, eye and respiratory devices when operating the TCB.
- TCB should be stored in a dry, cool, well-ventilated place, away from ignition and other flammable substances.
-In the event of accidental contact with TCB, immediately rinse the skin with plenty of water and seek medical assistance. If TCB is inhaled or taken by mistake, take the patient to the hospital immediately.
Last Update：2024-04-09 15:17:52
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